The U.S. Department of State has a long-standing Worldwide Caution that has been in effect for over a decade. It is updated regularly with the most recent recommendations for international travel. This latest update was issued on January 15, 2019. Read the Worldwide Caution.
The U.S. Dept. of State issues Travel Advisories for all countries in the world. Check out the advisory for your destination country. Also, enroll in the STEP Program to receive additional security alerts during your trip through your email.